In the beginning of 2001, the Research and Development sector, entitled " Research Institute for Social Cultural and Environment Development has been established based on the foundations of research of the Thai study. This sector used  the  " Bottom up " approach drafted by Professor Emeritus Dr. Chonthira Sattayawattana who has been appointed as the first Director of the Research. Subsequently, Dr. Chonthira Sattayawattana certified and approved to operate according to the vision , mission and strategic plan of the proposed work plan for the University Council . The resolution of the Council at that time had approved the arrangement of the Administrative sector focusing on R & D (Research and Development) to support, promote and develop the research and development of the university. Hence, providing academic excellence, services to the public and community outreach in accordance with the Education Act 1999. It was conducted according to the guidelines of the Institute until present.

         Initially, the original “Research Institute” was managed under the university funds which is divided into Basic Knowledge and Applied Research sectors. These two sectors were, namely, "Research Institute" and “Research Institute for Development" operating in the administrative structure of the university under the advice of the Vice President of Academic Affairs, Prof. Dr. Theerayut Klinsukon.

           By end of the year 2002, the university had merged the two sectors which were managed under the three research approaches: 1) Basic Research, 2) Applied Research and 3) Research and Development by the Research Institute. On September 19, 2002, the two merged sectors were renamed as Rangsit Research Institute.

      Later the institute had developed a new structure in management, moving from the initial “Network Line” approach to the “Command Line” approach. This new approach formed a research network recruiting dedicated researchers and formed 6 new networks and 1 project which are: 1)   Centre for Social Sciences Research, 2) Centre for Thailand - Asian Studies, 3) Centre for Technology Research for Rural Development, 4) Centre for Health Sciences, 5) Centre for Environmental and Natural Resources and 6) Centre for Energy and Resources and one project for establishment of the Center for Media and Cultural Studies. The Centre for Social Sciences Research and Thai Studies, formed prior to the Research Institute, had laid a strong research foundation in conveying important concepts. The interdisciplinary research paradigm has been integrated to increase experience in research management. This had led to the search for funding from external sources, both national and international which has become a guiding principle in developing the growth of the Research Institute and Quality Assurance.

          In the late 2003, the university had assigned the Office of Planning and Development and Centre for Support and Teaching Development to provide internal funding for research in developmental teaching and learning. The management structure was based on “line supervision " and there is no coordination or management of joint research funding between each sector. To modify the structure of the institute's administration, in 2004 the director of the Research Institute was change to Dr. Pongjan Yoopat, the present director and appointed various committees including the Advisory Board, Executive Committee, Technical Committee, Human Ethics Committee, Animal Ethics Committee, and Biosafety Committee. Rangsit University is responsible for the validation of research projects and coordinates with the central committee of the related issues and form guidelines of the Research Institute under the 6 research networks and 1 project to improve management and budgets that focused on obtaining external funding.

         On February 5, 2007, the Research Institute was abolished, following the establishment of two new institutes: 1) The Institute of Science and Technology under the supervision of Asst. Prof. Dr. Pongjan Yoopat and 2) Social Science Research Institute under the supervision of Prof. Emeritus Dr. Chonthira Sattayawattana. These two institutes were placed under the supervision of the Vice President for Research. 

         On June 12, 2007, the Institute of Science and Technology and the Institute of Social Sciences had moved under the supervision of the Vice President for Academic Affairs. Later on June 22, both institutes were dissolved and the new Research Institute was established under the supervision of Asst. Dr. Pongjan Yoopat.

         The Research Institute was moved to the supervision of the Vice Presidents of Research and Academic Service Affairs on March 29, 2013 with Asst. Prof. Dr. Pongjan Yoopat as the director.